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Einstein (Säo Paulo) ; 18: eRC5522, 2020.
Article in English | LILACS | ID: biblio-1142879

ABSTRACT

ABSTRACT We report a case of a 61-years-old woman in remission of psoriasis for 20 years. She presented recurrence of psoriasis in the form of plaques few days after taking L-methylfolate 15mg/day. The L-methylfolate was prescribed as an adjuvant for the treatment of depression in a patient with the methylenetetrahydrofolate reductase gene polymorphism (MTHFR).


RESUMO Paciente do sexo feminino, 61 anos, em remissão da psoríase por 20 anos. Apresentou recidiva de psoríase em forma de placas poucos dias após início de tratamento L-metilfolato na dose diária de 15mg. O L-metilfolato foi prescrito como terapêutica coadjuvante para tratamento de depressão em paciente portadora do polimorfismo do gene metilenotetrahidrofolato redutase.


Subject(s)
Humans , Female , Psoriasis/chemically induced , Quality of Life , Tetrahydrofolates/administration & dosage , Methylenetetrahydrofolate Reductase (NADPH2)/deficiency , Depression/drug therapy , Homocystinuria/complications , Muscle Spasticity/complications , Polymorphism, Genetic , Psychotic Disorders/complications , Recurrence , Tetrahydrofolates/therapeutic use , Treatment Outcome , Methylenetetrahydrofolate Reductase (NADPH2)/genetics , Middle Aged
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